How Long Do Ketamine Infusions Stay in Your System?
Primary Keyword: how long do ketamine infusions last in the body
Secondary Keywords: ketamine metabolism, duration of ketamine effects, recovery after infusion
Meta Title: How Long Do Ketamine Infusions Stay in Your System? | KetaRevive
Meta Description: Discover how long ketamine remains active in your body, what affects recovery time, and how KetaRevive ensures safe, monitored care.
Introduction
One of the most common questions new patients ask is, “How long does ketamine stay in my system?” Understanding this helps set expectations and plan post-treatment recovery.
The Science of Ketamine Metabolism
Half-life: Intravenous ketamine has a short half-life—about 2.5 to 3 hours.
Clearance: The liver metabolizes ketamine into norketamine, which is excreted via urine within 24 hours.
Brain activity: Even after the drug clears, its neurochemical effects—especially on NMDA receptors—can continue for days, driving antidepressant benefits.
Phase/Typical Duration/What You May Feel
During infusion
40–60 minutes
Floating, lightness, mild dissociation
Phase/Typical Duration/What You May Feel
Post-infusion calm
2–6 hours
Relaxed, reflective, sometimes tired
Phase/Typical Duration/What You May Feel
Therapeutic benefit
3–14 days
Mood elevation, reduced pain, increased focus
Factors That Influence Clearance
Dosage and infusion rate
Individual metabolism
Hydration and liver function
Concurrent medications
Safety & Monitoring at KetaRevive
At KetaRevive, vital signs are tracked throughout treatment, and patients remain on-site until fully alert. Follow-up instructions include hydration, rest, and optional check-ins within 24 hours.
Takeaway
Although ketamine itself leaves the body quickly, its healing impact lasts much longer. KetaRevive focuses on both phases—ensuring rapid, monitored clearance and lasting wellness after each infusion.
